Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
All Product Categories
-
Parasite Related Products (2505)
Related Products (2505)
-
Related Compound Screening Libraries (1)
-
Parasite Isoform Comparison
-
7-Methoxy-β-carboline-1-propionic acid
0 ImagesCat. No.: HY-N7173CAS No.: 137756-13-97-Methoxy-β-carboline-1-propionic acid (compound 46) is a cytotoxic and antimalarial compound. 7-Methoxy-β-carboline-1-propionic acid can be extracted from the roots of Eurycoma longifolia.
-
Nemadectin (90%)
0 ImagesCat. No.: HY-112542ACAS No.: 102130-84-7Synonyms: CL-287088 (90%); LL-F28249 α (90%)Nemadectin (90%) (CL-287088 (90%)), an orally active broad-spectrum endectocide and macrolide antibiotic. Nemadectin shows anthelmintic activity against T. canis, A. caninum and U. stenocephala.
-
Apoptosis inducer 53
0 ImagesCat. No.: HY-179451Apoptosis inducer 53 is an apoptosis inducer. Apoptosis inducer 53 can inhibit proliferation of human tumor cell lines (A549, HeLa, SW1573, T-47D, WiDr) with GI50 values of 2.5-9.1 μM. Apoptosis inducer 53 can induce cancer cells apoptosis and reduce colony formation. Apoptosis inducer 53 can activate p38α MAPK signaling and exerts anti-inflammatory effect. Apoptosis inducer 53 also shows anti-Leishmania donovani activity. Apoptosis inducer 53 can be used for the researches of cancer, infection and inflammation.
-
Nitenpyram (Standard)
0 ImagesNitenpyram (Standard) is the analytical standard of Nitenpyram. This product is intended for research and analytical applications. Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals.
-
5'-Methylthioadenosine-13C
0 ImagesCat. No.: HY-W753201Synonyms: 5'-(Methylthio)-5'-deoxyadenosine-13C; 5'-Deoxy-5'-(methylthio)adenosine-13C; 5'-S-Methyl-5'-thioadenosine-13C5'-Methylthioadenosine-13C (5'-(Methylthio)-5'-deoxyadenosine-13C) is the 13C-labeled 5'-Methylthioadenosine (HY-16938). 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis.
-
Odoratone
0 ImagesCat. No.: HY-N3156CAS No.: 16962-90-6Synonyms: DehydroodoratolOdoratone (Dehydroodoratol) has insecticidal activity (LC50: 154 ppm).
-
Antitrypanosomal agent 11
0 ImagesCat. No.: HY-151943Antitrypanosomal agent 11 is an antitrypanosomal agent that inhibits Trypanosoma cruzi with an IC50 of 0.23 μM.
-
DXR-IN-1
0 ImagesCat. No.: HY-158335DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity.
-
LmCPB-IN-1
0 ImagesCat. No.: HY-146649CAS No.: 2151025-98-6LmCPB-IN-1 (compound 35) is a potent and reversible covalent Leishmania mexicana cysteine protease B (LmCPB) inhibitor with a pKi of 9.7.
-
Cyclobenzaprine
0 ImagesCyclobenzaprine (MK130) is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Cyclobenzaprine also possesses antiparasitic activity. Cyclobenzaprine holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases.
-
Antimalarial agent 36
0 ImagesCat. No.: HY-161170CAS No.: 2982633-03-2Antimalarial agent 36 (compound 1) is an antimalarial agent, with the EC50s of 58 nM and 42 nM, for Dd2 and 3D7, respectively. Antimalarial agent 36 targets EphA2.
-
Epsiprantel
0 ImagesCat. No.: HY-U00045CAS No.: 98123-83-2Synonyms: BRL-38705Epsiprantel (BRL-38705) is a compound with anti-Echinococcus activity that can cause the death of protoscolex, larvae and adults in vitro, and is more effective against mature worms than larvae in vivo, with no side effects.
-
Pyriproxyfen-d4
0 ImagesCat. No.: HY-B2031S1CAS No.: 2446366-95-4Synonyms: S-31183-d4Pyriproxyfen-d4 (S-31183-d4) is the deuterium labeled Pyriproxyfen. Pyriproxyfen is a juvenile hormone analog and insect growth regulator. Pyriproxyfen is used in research related to dengue fever and malaria.
-
Benznidazole-d7
0 ImagesCat. No.: HY-B1548SSynonyms: Benznidazol-d7; Ro 07-1051-d7; Ro 71051-d7Benznidazole-d7 (Benznidazol-d7; Ro 07-1051-d7; Ro 71051-d7) is the deuterium labeled Benznidazole (HY-B1548). Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.
-
Sulfaquinoxaline (Standard)
0 ImagesSulfaquinoxaline (Standard) is the analytical standard of Sulfaquinoxaline. This product is intended for research and analytical applications. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections.
-
Isochamaejasmin
0 ImagesCat. No.: HY-N3497CAS No.: 93859-63-3Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells. Isochamaejasmin also has a moderate antiplasmodial activity (IC50 of 7.3 μM for P. falciparum) and relatively low cytotoxicity (CC50 of 29.0 μM).
-
Moxidectin (Standard)
0 ImagesCat. No.: HY-B0777RCAS No.: 113507-06-5Synonyms: CL301423 (Standard)Moxidectin (Standard) is the analytical standard of Moxidectin. This product is intended for research and analytical applications. Moxidectin (CL301423) is an orally active macrolide (ML) anthelmintic for the prevention and control of heartworms and roundworms. Moxidectin is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite mediated by Bcrp1 and P-gp. This may be related to the presence of chemical residues in milk.
-
Flufenamic acid-d4
0 ImagesCat. No.: HY-B1221SCAS No.: 1185071-99-1Flufenamic acid-d4 is deuterium labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
